Table 3

Risk factors for mortality in sepsis cohort

Variable	Reference	Univariate analysis		Multivariate analysis
Variable	Reference	HR (95% CI)	P value	HR (95% CI)	P value
Birth weight*
Extremely low birth weight (<1000 g)	Normal birth weight (>2500 g)	4.301 (1.47 to 12.61)	0.0078	3.60 (1.11 to 11.71)	0.033
Low birth weight (1000–<2500 g)	Normal birth weight (>2500 g)	0.783 (0.28 to 2.17)	0.6384	0.96 (0.32 to 2.88)	0.946
Sepsis pathway followed
Yes	No	0.79 (0.22 to 2.79)	0.709
Blood culture sent
Yes	No	0.532 (0.21 to 1.37)	0.1916
HIE
Yes	No	1.178 (0.49 to 2.84)	0.716
Maternal illness at time of delivery
Yes	No	0.841 (0.195 to 3.62)	0.8163
Congenital deformity
Yes	No	1.692 (0.39 to 7.02)	0.477
Sex
Male	Female	0.834 (0.37 to 1.88)	0.6618
HIV exposure
Yes	No	0.5 (0.15 to 1.69)	0.2657
Born at home
Yes	No	2.556 (0.59 to 11.08)	0.2098
Mode of delivery
C-section	Vaginal	0.532 (0.198 to 1.43)	0.21
Critically ill
Yes	No	3.517 (1.54 to 8.04)	0.003	2.39 (1.0 to 5.77)	0.05
Sepsis pathway followed
Yes	No	0.786 (0.22 to 2.79)	0.709
Drug shortages
Yes	No	1.80 (0.53 to 6.09)	0.35
Appropriate antibiotics on admission
No	Yes	1.90 (0.82 to 4.38)	0.13	0.58 (0.25 to 1.35)	0.207
Blood culture sent
Yes	No	0.532 (0.21 to 1.37)	0.19