Age-specific and sex-specific risks of al-cause mortality during the use of methylphenidate
| Characteristic | Cases/controls (n) | HR (95% CI) |
| Women | 375/44 077 | 1.7 (1.2 to 2.5) |
| Men | 571/52 154 | 1.1 (0.8 to 1.5) |
| 18–40 years of age | 67/62 478 | 1.2 (0.4 to 3.5) |
| 41–60 years of age | 240/28 191 | 1.1 (0.7 to 1.8) |
| 61–80 years of age | 412/4781 | 1.6 (1.2 to 2.2) |
| >80 years of age | 227/721 | 1.2 (0.7 to 2.0) |
All HRs are adjusted for sex, age, smoking, hypertension, diabetes mellitus, BMI, hypercholesterolemia, decreased renal function and ‘intention-to-treat’
BMI, body mass index.