Trends of venous thromboembolism risks by stratified follow-up years
| Control (N=26 944) | Early eradication (N=3062) | IRR (95% CI) | Adjusted HR† | Late eradication (N=3674) | IRR (95% CI) | Adjusted HR† | ||||
| Follow-up time, years | Case | Rate* | Case | Rate* | (95% CI) | Case | Rate* | (95% CI) | ||
| ≤5 | 216 | 2.08 | 42 | 3.41 | 1.64 (1.46 to 1.84)‡ | 1.92 (1.38 to 2.68)‡ | 165 | 12.1 | 5.81 (5.41 to 6.24)‡ | 4.21 (3.41 to 5.20)‡ |
| >5 | 198 | 5.19 | 12 | 2.21 | 0.43 (0.33 to 0.54)‡ | 0.44 (0.24 to 0.78)‡ | 107 | 25.4 | 4.90 (4.45 to 5.40)‡ | 3.45 (2.69 to 4.43)‡ |
| ≤5 | 1 (reference) | 1 (reference) | 3.54 (3.00 to 4.18)‡ | 2.41 (1.70 to 3.41)‡ | ||||||
| >5 | 1 (reference) | 1 (reference) | 11.5 (8.43 to 15.8)‡ | 7.92 (4.27 to 14.7)‡ | ||||||
*Incidence rate per 1000 person-years.
†Multiple analyses including age, sex, and comorbidities of hypertension, diabetes, hyperlipidaemia, coronary artery disease, heart failure, cancer, stroke, and lower leg fracture or surgery.
‡P<0.001.
IRR, incidence rate ratio.