HRs of venous thromboembolism between early and later Helicobacter pylori eradication
| Early eradication | Late eradication | |||
| IRR (95% CI) | Adjusted HR* | IRR (95% CI) | Adjusted HR* | |
| (95% CI) | (95% CI) | |||
| All | 1 (reference) | 1 (reference) | 5.00 (4.25 to 5.90)† | 3.56 (2.63 to 4.81)† |
| Gender | ||||
| Female | 1 (reference) | 1 (reference) | 6.52 (4.98 to 8.54)† | 4.05 (2.57 to 6.38)† |
| Male | 1 (reference) | 1 (reference) | 3.57 (2.91 to 4.38)† | 2.83 (1.86 to 4.31)† |
| Age | ||||
| ≤49 | 1 (reference) | 1 (reference) | 0.65 (0.51 to 0.82)† | 0.84 (0.43 to 1.67) |
| 50–65 | 1 (reference) | 1 (reference) | 5.37 (4.03 to 7.17)† | 3.50 (2.18 to 5.60)† |
| ≥65 | 1 (reference) | 1 (reference) | 14.9 (7.77 to 28.7)† | 16.5 (6.05 to 45.3)† |
| Comorbidity | ||||
| No | 1 (reference) | 1 (reference) | 0.83 (0.66 to 1.05) | 0.83 (0.42 to 1.62) |
| Yes | 1 (reference) | 1 (reference) | 5.70 (4.41 to 7.37)† | 5.38 (3.64 to 7.97)† |
*Multiple analyses including age, sex, and comorbidities of hypertension, diabetes, hyperlipidaemia, coronary artery disease, heart failure, cancer, stroke, and lower leg fracture or surgery.
†P<0.00.
IRR, incidence rate ratio.