Population, Intervention, Comparison, Outcome and Study Design (PICOS) strategy and inclusion and exclusion criteria
| PICOS item | Inclusion criteria | Exclusion criteria |
| Population | Solid-organ and haematopoitic stem cell transplant candidates and recipients tested for strongyloidiasis. Including children (less than 18 years of age) and/or adults who are migrants, travellers and residents of Strongyloides endemic and non-endemic areas. | Studies that do not report specifically on Strongyloides. Studies reporting on immunocompromised population without reporting specifically on SOT or HSCT candidates or recipients. |
| Intervention | Diagnosis of Strongyloides must be confirmed through either stool-based methods or serology. | Diagnostic methods other than the recognised Strongyloides diagnostic methods |
| Comparator | A comparator is not applicable. | |
| Outcomes | Prevalence of Strongyloides in SOT and HSCT candidates or recipients. Mortality rate of hyperinfection and disseminated strongyloidiasis in in SOT and HSCT candidates or recipients. | Studies that do not report on the prevalence and or on the cases of severe strongyloidiasis will be excluded. |
| Study Design | Case reports, case-series, observational and interventional studies (if any). | Animal studies |
HSCT, haematopoietic stem cell transplant; SOT, solid-organ transplant.