Table 1

Population, Intervention, Comparison, Outcome and Study Design (PICOS) strategy and inclusion and exclusion criteria

PICOS itemInclusion criteriaExclusion criteria
PopulationSolid-organ and haematopoitic stem cell transplant candidates and recipients tested for strongyloidiasis. Including children (less than 18 years of age) and/or adults who are migrants, travellers and residents of Strongyloides endemic and non-endemic areas.Studies that do not report specifically on Strongyloides. Studies reporting on immunocompromised population without reporting specifically on SOT or HSCT candidates or recipients.
InterventionDiagnosis of Strongyloides must be confirmed through either stool-based methods or serology.Diagnostic methods other than the recognised Strongyloides diagnostic methods
ComparatorA comparator is not applicable.
OutcomesPrevalence of Strongyloides in SOT and HSCT candidates or recipients.
Mortality rate of hyperinfection and disseminated strongyloidiasis in in SOT and HSCT candidates or recipients.
Studies that do not report on the prevalence and or on the cases of severe strongyloidiasis will be excluded.
Study DesignCase reports, case-series, observational and interventional studies (if any).Animal studies
  • HSCT, haematopoietic stem cell transplant; SOT, solid-organ transplant.