Table 1

Trial schedule and assessments at different time points

Study period
Time pointED arrivalEnrolmentAllocationPost-interventionClose-out
1 hour2 hours4 hours12 hours24 hours48 hours72 hours
Trial process
 Eligibility screenX
 Informed consentX
 Patients’ demographicsX
 Respiratory rateXXXXXXXXX
 Blood pressureXXXXXXXXX
 Pulse rateXXXXXXXXX
 Pulse oximetryXXXXXXXXX
 GCS scoreXXXX
 Arterial blood gasXX
 MBS scoreXXX
 Lung ultrasound scoreXXX
 Treatment failurex
 Hospital length of stayx
  • FiO2, fraction of inspired oxygen; GCS, Glasgow Coma Scale; HFNC, high-flow nasal cannula; MBS, modified Borg Scale; NIPPV, non-invasive positive pressure ventilation.