Table 4

Logistic regression analysis of patients with and without adverse drug reactions

Univariable OR
(95% CI)
P value
(Wald χ2)
Multivariable OR
(95% CI)
P value
(Wald χ2)
Age1.02 (1.01 to 1.03)<0.0011.02 (1.01 to 1.03)<0.001
Sex (male)1.07 (0.80 to 1.44)0.659
Number of medicines1.11 (1.07 to 1.14)<0.0011.10 (1.07 to 1.13)<0.001
Number of comorbidities1.08 (1.04 to 1.13)<0.001
Liver impairment (CLD)2.58 (1.35 to 4.93)0.0043.23 (1.63 to 6.40)<0.001
Renal impairment (CKD stage IV or V)1.69 (1.04 to 2.78)0.036
  • CKD, chronic kidney disease; CLD, chronic liver disease.