Table 1

Suggested study designs for inclusion in the review

Suggested termsDefinitionNotes
Randomised controlled trial (RCT) OR randomised trialAn experimental study in which people are allocated to different interventions using methods that are random.We will consider both individual and cluster randomised trials. We also consider the factorial design trials
Non-randomised controlled trial (NRCT) OR non-randomised trialAn experimental study in which people are allocated to different interventions using methods that are not random.We will use consistent terminology and avoid using the term quasi-experimental as it might have different meanings in different settings. We will use the ROBINS-1 for risk of bias assessment for this study design
Controlled before-after study (CBA)A study in which observations are made before and after the implementation of an intervention, both in a group that receives the intervention and in a control group that does not.We will require two minimum criteria for the inclusion of CBAs.
  • Data Collection: We will include CBAs if the data for the intervention and control groups were collected prospectively in the same time frame

  • Choice of Control: We will include CBAs that include a control at a second site to avoid contamination of the intervention to the control group if the settings and populations are the same for the intervention and control groups.