Table 2

Inclusion and exclusion criteria for recipients of FMT

InclusionAdults 18–65 years
Diagnosed with IBS-D or IBS-M according to the rome IV criteria
Expected adherence to following the protocol
Written consent to the study
ExclusionThe use of antibiotics and probiotics within 1 month prior to faecal microbiota transplantation
History of inflammatory bowel disease or gastrointestinal malignancy, systemic autoimmune diseases (ongoing or in history)
Previous abdominal surgery (other than appendectomy or cholecystectomyor hernioplasty or caesarean section)
HIV infection or other active infection
Renal or hepatic disease (both defined by biochemistry workup)
Diabetes mellitus, abnormal thyroid functions not controlled by thyroid medications
Bipolar disorder or schizophrenia (ongoing or history thereof), moderately severe depression defined by Patient Health Questionnaire-9 score >15
Anxiety defined by a Generalised Anxiety Disorder 7 score >10, with any organic causes that can explain the symptoms of IBS
Current pregnancy and lactation
  • FMT, faecal microbiota transplantation; IBS, irritable bowel syndrome.