Table 2

Potential candidate predictors organised in domains.

DomainsPotential predictors
Demographics
  1. Age at implantation

  2. Gender

  3. Social economic status

  4. Highest education level

Tinnitus characteristics
  1. Pre-implantation tinnitus impact multi-item or single-item validated questionnaire

  2. Tinnitus duration at the time of the implantation

  3. Tinnitus localisation

  4. Tinnitus pitch-matched

  5. Tinnitus loudness-matched

  6. Tinnitus temporal pattern (constant or intermittent)

Hearing characteristics
  1. Pre-implantation speech perception scores in quiet

  2. Pre-implantation speech perception scores in noise

  3. Pre-implantation hearing level in the future implanted ear (including means and per frequencies ranging from 125 Hz to 20 kHz)

  4. Pre-implantation hearing level in the contralateral ear (including means and per frequencies ranging from 125 Hz to 20 kHz)

  5. Pre-implantation subjective hearing disability measure (total score) assessed by a multi-item or single-item validated questionnaire, holding outcomes on one or multiple domains covering body function, activity limitations and participation restrictions, environmental factors and personal factors48 49

  6. Pre-implantation electrophysiological outcomes (ABR or ECochG)

Imaging
  1. Cochlear anatomy limiting cochlear implant performance based on imaging (eg, cochlear ossification, cochlear dysplasia)

Comorbidities
  1. Hyperacusis presence

  2. Depression symptoms assessed by a multi-item or single-item validated questionnaire

  3. Anxiety symptoms assessed by a multi-item or single-item validated questionnaire

  4. Stress symptoms assessed by a multi-item or single-item validated questionnaire

  5. Personality assessed by a multi-item or single-item validated questionnaire

  6. Coping strategies assessed by a multi-item or single-item validated questionnaire

  7. Measure of general health assessed by a multi-item or single-item validated questionnaire

  8. Measure of quality of life assessed by a multi-item or single-item validated questionnaire

  9. Measure of sleep quality assessed by a rating

  10. Cardiovascular disease presence diagnosed by a clinician

  11. Metabolic disease presence diagnosed by a clinician

  12. Neurological disease presence diagnosed by a clinician

Treatment
  1. Hearing aid use in the future implanted ear

  2. Hearing aid use in the contralateral ear