Sample size calculation
| Incidence* in both groups under H1 | Incidence* in the exposed group under H0 | Power | Size in each group | Total size |
| 150 | 450 | 50% | 901 | 1802 |
| 60% | 1200 | 2400 | ||
| 70% | 1566 | 3132 | ||
| 80% | 2059 | 4118 | ||
| 90% | 2852 | 5704 | ||
| 400 | 1200 | 50% | 337 | 674 |
| 60% | 449 | 898 | ||
| 70% | 586 | 1172 | ||
| 80% | 771 | 1542 | ||
| 90%† | 1067 | 2134 | ||
| 750 | 2250 | 50% | 567 | 1134 |
| 60% | 410 | 820 | ||
| 70% | 312 | 624 | ||
| 80% | 239 | 478 | ||
| 90% | 180 | 360 |
*Weekly incidence per 100 000 individuals (considered as identical to the probability of a SARS-CoV-2 infection in the general population).
†Power calculation stated in the COVID-ESO study protocol.