Table 1

Participant timeline

Study period
Time point	Enrolment	Allocation	Postallocation
Time point	Preoperative	0 day	Surgery	0.5 hour	1 hour	2 hours	4 hours	8 hours	12 hours	24 hours	2 days	3 days	4 days	5 days
Enrolment	X
Eligibility screen	X
Informed consent	X
Random allocation		X
Interventions
Baseline data		X
Systemic lidocaine			X
Intraoperative data			X
Assessments
POD and severity									X	X	X	X	X	X
NRS pain score				X	X	X	X	X	X	X	X
Emergence agitation				X	X
Postoperative opioid consumption										X	X
QoR-15		X								X	X
Patient satisfaction											X
PONV				X	X	X	X	X	X	X	X
Dizziness				X	X	X	X	X	X	X	X
Time to first bowel movement				X	X	X	X	X	X	X	X	X
Time to first passage of flatus				X	X	X	X	X	X	X	X	X
Time of first analgesia demand				X	X	X	X	X	X	X	X

NRS, Numeric Rating Scale; POD, postoperative delirium; PONV, postoperative nausea and vomiting; QoR-15, 15-item quality of recovery questionnaire.