Table 2

Pro Survey

1. In the last 7 days, how often did you have nausea?
Never	Rarely	Occasionally	Frequently	Almost constantly
2. In the last 7 days, how often did you have loose or watery stools (diarrhea/diarrhoea)?
Never	Rarely	Occasionally	Frequently	Almost constantly
3. In the last 7 days, what was the severity of your constipation at its worst?
None	Mild	Moderate	Severe	Very severe
4. In the last 7 days, what was the severity of your pain at its worst?
None	Mild	Moderate	Severe	Very severe
5. In the last 7 days, how much did your shortness of breath interfere with your usual or daily activities?
Not at all	A little bit	Somewhat	Quite a bit	Very much
6. In the last 7 days, how often did you have sad or unhappy feelings?
Never	Rarely	Occasionally	Frequently	Almost constantly
7. In the last 7 days, how often did you feel anxiety?
Never	Rarely	Occasionally	Frequently	Almost constantly
8. Over the past week I would generally rate my activity as
0, normal with no limitations
1, not my normal self, but able to be up and about with fairly normal activities
2, not feeling up to most things, but in bed or chair less than half the day
3, able to do little activity and spend most of the day in bed or a chair
4, pretty much bedridden, rarely out of bed