Table 1

Comorbidity categories and their definitions in terms of ATC codes, number of individuals aged 65 years and older in each comorbidity category,* crude 1-year mortality risk, adjusted mortality ORs and assigned weights

	Category	ATC codes†	All	Men	Women	% died in 2014	OR‡	Weight
0	Drugs not mapped to a comorbidity category		37 892	17 046	20 846	1.4	–	–
1	Alcohol dependency	N07BB§	2 909	1 330	1 579	4.1	1.75	4
2	Allergies	R01AC§ R01AD§ R06AD02 R06AD03 R06AE§ R06AX§ R06AB§	107 407	39 982	67 425	2.7	0.81	−1
3	Anticoagulants	B01AA§ B01AB§ B01AE07 B01AF§ B01AX§	97 138	52 098	45 040	6.3	1.31	2
4	Antiplatelets	B01AC§	266 586	139 584	127 002	3.8	1.09	1
5	Anxiety	N05BA§ N05BE§	94 527	26 603	67 924	5.4	1.31	2
6	Arrhythmia	C01AA§ C01B§	25 205	13 225	11 980	7.7	1.36	2
7	Benign prostatic hyperplasia (men)	G04C§	47 685	47 685	–	3.9	0.79	−1
8	Bipolar disorder	N05AN01	1 923	762	1 161	3.8	1.41	3
9	Chronic airways disease	R03§	108 979	46 692	62 287	4.6	1.39	2
10	Congestive heart failure	C03DA§ C07AB07 C07AG02	39 553	20 383	19 170	7.1	1.57	3
11	Dementia	N06DA§ N06DX01	13 871	5 109	8 762	9.9	2.10	6
12	Depression	N06A§	88 075	25 662	62 413	5.2	1.27	2
13	Diabetes	A10§	76 319	41 249	35 070	4.3	1.35	2
14	Epilepsy	N03A§	30 981	12 830	18 151	5.9	1.46	3
15	Glaucoma	S01E§	55 466	22 831	32 635	4.2	0.90	−1
16	Gastro-oesophageal reflux disease	A02B§ except A02BX12	157 384	65 725	91 659	4.8	1.21	2
17	Gout	M04§	29 515	19 808	9 707	6.3	1.15	1
18	Hepatitis B	J05AF08 J05AF10 J05AF11	n/r	n/r	n/r	0	0.00¶	0
19	Hepatitis C	J05AP§ L03AB10 L03AB11 J05AB54 J05AB60 J05AB61 J05AE14 J05AE11 J05AE12 J05AX14 J05AX15 J05AX65 J05AB04	n/r	n/r	n/r	3.6	0.76¶	0
20	HIV	J05AE§ J05AF12 J05AF13 J05AG§ J05AR§ J05AX07 J05AX08 J05AX09 J05AX12 J05AF01 J05AF02 J05AF03 J05AF04 J05AF05 J05AF06 J05AF07 J05AF09	184	n/r	n/r	3.8	2.16	6
21	Hyperkalaemia	V03AE01 V03AE10	305	216	89	16.4	1.72	4
22	Hyperlipidaemia	C10§	297 164	146 741	150 423	2.8	0.74	−1
23	Hypertension	C03A§ C03B§ C03DB§ C03EA§ C09BA§ C09DA§ C02A§ C02DB§ C03C§ C09C§	310 471	134 422	176 049	4.1	1.15	1
24	Hyperthyroidism	H03B§	1 842	333	1 509	4.7	1.22	2
25	Hypothyroidism	H03A§	80 643	16 057	64 586	3.2	0.91	−1
26	Irritable bowel syndrome	A07EA§ A07EC§ L04AA33	6 432	2 891	3 541	2.9	0.83	−1
27	Ischaemic heart disease: angina	C01D§ C08EX02	50 804	25 177	25 627	6.5	1.10	1
28	Ischaemic heart disease: hypertension	C07AA03 C07AA05 C07AA06 C07AA12 C07AB02 C07AB03 C07AG01 C08CA01 C08CA02 C08CA03 C08CA05 C08CA06 C08CA13 C08DA01 C08DB01 C09BB02 C09DB01 C09DB02 C09DX01	301 220	144 844	156 336	4.0	1.05	1
29	Incontinence	G04BD§	32 357	10 595	21 762	3.6	0.95¶	0
30	Inflammation/pain	M01A§	164 036	65 587	98 449	1.9	0.63	−1
31	Liver failure	A06AD11 A07AA11	6 752	3 072	3 500	22.1	3.91	6
32	Malignancies	L01§	3 398	1 656	1 742	25.0	8.06	6
33	Malnutrition	B05BA§	148	65	83	35.1	8.11	6
34	Migraine	N02C§	8 452	1 656	6 796	1.1	0.60	−1
35	Osteoporosis	M05B§ G03XC01 H05AA02 H05BA01	46 086	4 857	41 229	4.3	1.02¶	0
36	Pain	N02A§ N02B§	223 043	79 671	143 372	5.4	1.68	4
37	Pancreatic insufficiency	A09AA02	2 497	1 025	1 472	9.1	2.30	6
38	Parkinson’s disease	N04A§ N04B§	11 387	5 529	5 858	5.7	1.38	2
39	Psoriasis	D05§	8 208	4 364	3 844	3.2	1.13	1
40	Psychotic illness	N05A§ except N05AN01	25 515	8 822	16 693	6.4	1.50	3
41	Pulmonary hypertension	C02KX§	46	n/r	n/r	15.2	7.96	6
42	Renal disease	B03X§ A11CC03 A11CC04 V03AE§ except V03AE01 and V03AE10	4 612	2 643	1 969	13.8	2.55	6
43	Smoking cessation	N07BA§	3 356	1 570	1 786	3.5	1.58	3
44	Steroid-responsive disease	H02§	75 191	31 153	44 038	7.3	1.93	5
45	Transplant	L04AA06 L04AA10 L04AA18 L04AD01 L04AD02	1 653	1 040	613	7.4	1.37	2
46	Tuberculosis	J04A§	278	136	142	7.9	1.97	5

The Norwegian Prescription Database population aged 65 years and older in 2013
*Defined by at least one dispensed prescription drug in outpatient pharmacies in Norway in 2013, conditioned on survival through 2013. The same individual may occur in one or more category. Numbers lower than 40 in total or in any sex stratum are not reported and replaced by n/r.
†WHO Collaborating Centre for Drug Statistics Methodology. ATC/DDD Index. https://www.whocc.no/atc_ddd_index/.
‡From a logistic regression model including age, sex and all comorbidity categories as indicator (0/1) variables.
§With all subcodes.
¶ p>0.10.
ATC, Anatomical Therapeutic Chemical.