HRs with 95% CIs for the association between PE in the first pregnancy, offspring birth weight and future risk of cardiovascular disease (CVD) in 618 644 Norwegian women.
| Total no/no with CVD | No with CVD per 1000 person years (95% CI) | Crude HR (95% CI) | Adjusted* HR (95% CI) | |
| Without PE, GH, LGA or SGA | 551 593/17 974 | 2.27 (2.23 to 2.99) | 1 (ref.) | 1 (ref.) |
| PE only | 27 051/1760 | 4.87 (4.65 to 5.10) | 2.21 (2.11 to 2.32) | 2.16 (2.05 to 2.26) |
| LGA only | 15 739/524 | 2.37 (2.18 to 2.58) | 1.09 (1.00 to 1.18) | 1.08 (0.99 to 1.18) |
| SGA only | 10 254/530 | 3.11 (2.85 to 3.38) | 1.31 (1.20 to 1.42) | 1.24 (1.14 to 1.35) |
| PE +LGA | 1125/85 | 5.74 (4.64 to 7.10) | 2.72 (2.20 to 3.36) | 2.57 (2.08 to 3.18) |
| PE +SGA | 1272/76 | 3.70 (2.96 to 4.64) | 1.60 (1.27 to 2.00) | 1.54 (1.23 to 1.93) |
The table is made by the authors and all permits are obtained.
*Adjustments made for year of delivery, marital status and maternal educational level.
GH, gestational hypertension; LGA, large for gestational age (offspring birthweight z-score >2.0); PE, pre-eclampsia; SGA, small for gestational age (offspring birthweight z-score <−2.0).