Table 2

Total pregnancies and their outcomes in valproate-treated women aged 14–45 years by conception year 2011–2018

YearWomen aged 14–45 prescribed valproate during year (N)Valproate-exposed pregnancies conceived during year (N)Valproate-exposed pregnancy rate (per 1000 treated women)
201145727015.3
201244156314.3
201341795914.1
201439524812.1
201535655014.0
201631703410.7
20172875217.3
20182430208.2
YearOutcome of valproate-exposed pregnancies (N, %)
Live birthMiscarriageStillbirthTermination of pregnancy
201152(74)7(10)0(0)11(16)
201252(83)3(5)0(0)8(13)
201340(68)7(12)0(0)12(20)
201433(69)2(4)0(0)13(27)
201538(76)6(12)0(0)6(12)
201626(76)0(0)0(0)8(24)
201719(90)1(5)0(0)1(5)
201814(70)1(5)0(0)5(25)