aHR | 95% CI | P value | ||
ACEi/ARB use | 0.56 | 0.36 | 0.88 | 0.01 |
Age, years | <0.001 | |||
18–40 | ref | – | – | – |
40–64 | 1.69 | 0.82 | 3.52 | |
65–74 | 4.07 | 2.10 | 9.24 | |
75 and older | 5.53 | 2.52 | 12.14 | |
Race: | 0.55 | |||
African American | 0.88 | 0.60 | 1.29 | |
Hispanic/Latino/Asian/other | 0.68 | 0.32 | 1.45 | |
White | ref | |||
Male | 1.43 | 0.97 | 2.10 | 0.07 |
Married | 0.91 | 0.63 | 1.34 | 0.64 |
Current smoker | 1.04 | 0.51 | 2.14 | 0.91 |
Body mass index, kg/m2: | 0.001 | |||
<18.5 | 1.91 | 0.63 | 5.79 | |
18.5–24 | ref | |||
25–29 | 1.39 | 0.81 | 2.37 | |
30 and above | 2.50 | 1.54 | 4.06 | |
Hypertension | 0.91 | 0.52 | 1.57 | 0.73 |
Coronary artery disease | 0.78 | 0.57 | 1.20 | 0.26 |
Chronic kidney disease | 0.87 | 0.54 | 1.38 | 0.54 |
Heart failure | 1.96 | 1.21 | 3.15 | 0.006 |
Diabetes | 1.07 | 0.62 | 1.84 | 0.98 |
COPD | 1.07 | 0.58 | 1.95 | 0.84 |
HIV | 1.51 | 0.76 | 3.03 | 0.23 |
Solid-organ transplant recipient | 1.56 | 0.61 | 3.96 | 0.35 |
Multivariable-adjusted Cox proportional hazards regression model.
ACEi, ACE inhibitor; aHR, adjusted HR; ARB, angiotensin receptor blocker; COPD, chronic obstructive pulmonary disease.