General traits between extrahepatic and intrahepatic cholangiocarcinoma
| Variable | Extrahepatic group (n=876) | Intrahepatic group (n=1194) | P value |
| Age (years) | 66.03±11.19 | 63.54±11.78 | <0.001 |
| Age | 0.001 | ||
| ≤60 years | 254 (29.00%) | 427 (35.76%) | |
| >60 years | 622 (71.00%) | 767 (64.24%) | |
| Sex | <0.001 | ||
| Male | 567 (64.73%) | 580 (48.58%) | |
| Female | 309 (35.27%) | 614 (51.42%) | |
| Race | 0.008 | ||
| Black | 57 (6.51%) | 85 (7.12%) | |
| White | 656 (74.89%) | 947 (79.31%) | |
| Others | 162 (18.49%) | 162 (13.57%) | |
| Unknown | 1 (0.11%) | 0 (0%) | |
| Marital status | 0.025 | ||
| Single | 240 (27.40%) | 382 (31.99%) | |
| Married | 609 (69.52%) | 763 (63.90%) | |
| Unknown | 27 (3.08%) | 49 (4.10%) | |
| Differentiation | <0.001 | ||
| Grade I | 97 (11.07%) | 105 (8.79%) | |
| Grade II | 368 (42.01%) | 510 (42.71%) | |
| Grade III | 274 (31.28%) | 305 (25.54%) | |
| Grade IV | 3 (0.34%) | 14 (1.17%) | |
| Unknown | 134 (15.30%) | 260 (21.78%) | |
| AJCC clinical stage | <0.001 | ||
| Stage I | 246 (28.08%) | 448 (37.52%) | |
| Stage II | 418 (47.72%) | 206 (17.25%) | |
| Stage III | 108 (12.33%) | 382 (31.99%) | |
| Stage IV | 68 (7.76%) | 117 (9.80%) | |
| Unknown | 36 (4.11%) | 41 (3.43%) | |
| T stage | <0.001 | ||
| T1 | 112 (12.79%) | 520 (43.55%) | |
| T2 | 242 (27.63%) | 275 (23.03%) | |
| T3 | 366 (41.78%) | 210 (17.59%) | |
| T4 | 124 (14.16%) | 143 (11.98%) | |
| Tx | 32 (3.65%) | 46 (3.85%) | |
| N stage | <0.001 | ||
| N0 | 474 (54.11%) | 933 (78.14%) | |
| N1 | 371 (42.35%) | 217 (18.17%) | |
| Nx | 31 (3.54%) | 44 (3.69%) | |
| M stage | 0.276 | ||
| M0 | 785 (89.61%) | 1046 (87.60%) | |
| M1 | 68 (7.76%) | 117 (9.80%) | |
| Mx | 23 (2.63%) | 31 (2.60%) | |
Bold P values indicate that the corresponding item has statistical significance.
AJCC, American Joint Committee on Cancer.