Table 2

Characteristics of the index ACS and in-hospital complications by TIMI risk score for secondary prevention (TRS2°P)

TRS2°P
n (%)High-risk
TRS2°P=3
(n=2710)
Very high-risk
TRS2°P=4
(n=1557)
Extremely high-risk
TRS2°P≥5
(n=1092)
P-value
STEMI on presentation1058 (39.1)510 (32.8)261 (23.9)<0.001
Grace score >140354 (19.4)383 (37.4)494 (65.2)<0.001
Peak Troponin I elevated984 (74.8)583 (77.8)438 (82)<0.001
Admission Killip class I2128 (80)1077 (70.3)596 (56.1)<0.001
Admission Killip class II293 (11)256 (16.7)266 (25)<0.001
Admission Killip class III183 (6.9)169 (11)172 (16.2)<0.001
Admission Killip class IV56 (2.1)30 (2)29 (2.7)0.34
HR (BPM) (median (IQR))80(68, 94)80(68, 96)83(70, 100)<0.001
SBP (mm Hg) (median (IQR))144(125, 163)144(123, 165)141.5(122, 165)0.222
DBP (mm Hg) (median (IQR))80(70, 90)79(68, 90)77(66, 90)<0.001
NSR2329 (85.9)1272 (81.7)852 (78)<0.001
AF/ SVT169 (7.1)131 (9.6)107 (11.7)<0.001
Normal EF (>50%)875 (41)392 (32.6)213 (26)<0.001
Mild EF (40%–50%)605 (28.3)349 (29)205 (25)0.143
Moderate EF (30%–40%)422 (19.8)280 (23.3)215 (26.3)<0.001
Severe EF (<30%)233 (10.9)182 (15.1)186 (22.7)<0.001
In-hospital complications
CHF mild-moderate (Killip-2)254 (9.4)203 (13.1)238 (21.9)<0.001
Pulmonary oedema (Killip-3)240 (8.9)213 (13.7)190 (17.4)<0.001
Cardiogenic shock (Killip-4)135 (5)88 (5.7)67 (6.1)0.13
Post-MI angina/reischaemia114 (4.2)75 (4.8)54 (4.9)0.265
MR moderate-severe60 (2.2)45 (2.9)44 (4)0.002
New atrial fibrillation197 (7.3)129 (8.3)119 (10.9)<0.001
Asystole54 (2)56 (3.6)51 (4.7)<0.001
Stroke14 (0.5)16 (1)12 (1.1)0.035
Acute renal failure242 (9)220 (14.2)214 (19.7)<0.001
Bleeding44 (1.6)43 (2.8)34 (3.1)0.002
Blood transfusions38 (3.8)31 (5.3)44 (10.6)<0.001
  • ACS, acute coronary syndrome; AF/SVT, atrial fibrillation/supraventricular tachycardia; BPM, beats per minute; CHF, congestive heart failure; CVA, cerebrovascular accident; DBP, diastolic blood pressure; EF, ejection fraction; HR, heart rate; MI, myocardial infarction; MR, mitral regurgitation; NSR, normal sinus rhythm; SBP, systolic blood pressure; STEMI, ST-elevation myocardial infarction; TIMI, Thrombolysis in Myocardial Infarction.