Table 1

Baseline characteristics by TIMI risk score for secondary prevention (TRS2°P)


n (%)
TRS2°P
High-risk
TRS2°P=3
(n=2710)
Very high-risk
TRS2°P=4
(n=1557)
Extremely high-risk
TRS2P≥5
(n=1092)
P-value
Age, years (median (IQR))69 (60–78)75 (65–81)77 (69–82)<0.001
Gender (male)1889 (69.7)1076 (69.1)784 (71.8)0.3
Higher education249 (27.8)135 (25.4)68 (19.4)0.003
Hypertension2377 (87.7)1438 (92.4)1062 (97.3)<0.001
Diabetes mellitus1548 (57.1)1080 (69.4)881 (80.7)<0.001
Dyslipidaemia2005 (74.1)1206 (77.5)897 (82.3)<0.001
Current smoker990 (36.5)483 (31)345 (31.6)<0.001
PVD224 (8.3)322 (20.7)523 (47.9)<0.001
CKD*371 (13.7)466 (30)592 (54.3)<0.001
Family history of CAD514 (20.9)262 (18.9)145 (15.5)<0.001
Prior MI1029 (38.1)806 (51.9)715 (65.5)<0.001
Prior CABG328 (12.1)343 (22)510 (46.7)<0.001
Prior PCI971 (35.9)646 (41.6)568 (52.3)<0.001
Prior CHF195 (7.2)312 (20)558 (51.1)<0.001
Prior stroke296 (10.9)342 (22)422 (38.6)<0.001
Prior medications
Aspirin1641 (62.1)1090 (71.7)807 (76.3)<0.001
Clopidogrel325 (12.6)229 (15.3)250 (23.7)<0.001
Statins1486 (58.3)960 (65.4)747 (72.5)<0.001
ACEi839 (44.9)532 (48.9)365 (49.4)0.016
ARBs313 (17.3)218 (20.7)163 (23)0.001
Beta blockers1267 (48.7)889 (59.3)698 (67.1)<0.001
Nitrates366 (14.8)330 (23)328 (33.4)<0.001
  • *CKD was defined as eGFR< 60 mL/min by MDRD formula.

  • ACEi, angiotensin-converting enzyme inhibitors; ARBs, angiotensin receptor blockers; CABG, coronary artery bypass graft surgery; CAD, coronary artery disease; CHF, congestive heart failure; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; MDRD, Modification of Diet in Renal Disease; MI, myocardial infarction; PCI, percutaneous coronary intervention; PVD, peripheral vascular disease; TIMI, Thrombolysis in Myocardial Infarction.