Table 1

List of input variables

Input variablesMean valueDistributionDistribution parametersReference
Proportions of patients in different mRS states at the end of 3 months according to different studies
 MT alone DIRECT- MT13
 mRS 0–20.365Dirichlet0–1
 mRS 3–50.457Dirichlet0–1
 mRS 60.178Dirichlet0–1
 MT+alteplase 
 mRS 0–20.369Dirichlet0–1
 mRS 3–50.442Dirichlet0–1
 mRS 60.189Dirichlet0–1
 MT alone Bellwald et al11
 mRS 0–20.441Dirichlet0–1
 mRS 3–50.289Dirichlet0–1
 mRS 60.27Dirichlet0–1
 MT+alteplase 
 mRS 0–20.41Dirichlet0–1
 mRS 3–50.317Dirichlet0–1
 mRS 60.273Dirichlet0–1
 MT alone Coutinho et al12
 mRS 0–20.477Dirichlet0–1
 mRS 3–50.401Dirichlet0–1
 mRS 60.122Dirichlet0–1
 MT+alteplase 
 mRS 0–20.577Dirichlet0–1
 mRS 3–50.343Dirichlet0–1
 mRS 60.081Dirichlet0–1
Probabilities 
 Recurrent rate of stroke0.067BetaSD: 0.003
Range: 0.057–0.077		27
 RR of stroke recurrence per life-year1.03LognormalSD: 0.003
Range: 1.02–1.04		16
 RR of non-stroke death for mRS 3–51.68LognormalSD: 0.058
Range: 1.49–1.92		19 21
 mRS 0–2 to mRS 0–2 in first year0.955Dirichlet0–115
 mRS 0–2 to mRS 3–5 in first year0.024Dirichlet0–1
 mRS 3–5 to mRS 0–2 in first year0.03Dirichlet0–1
 mRS 3–5 to mRS 3–5 in first year0.946Dirichlet0–1
Costs (CNY) 
 MT treatment costs72 901GammaSD: 3959
Range: 62 704–84276		22
 Alteplase treatment costs13 399GammaSD: 255
Range: 12 651–14178		22
 One-time hospitalisation costs for mRS 0–210 882GammaSD: 173
Range: 10 478–11517		20
 One-time hospitalisation costs for mRS 3–513 510GammaSD: 225
Range: 13 016–14376		20
 One-time hospitalisation costs for mRS 611 887GammaSD: 201
Range: 11 415–12621		20
 Annual posthospitalisation costs for mRS 0–28852GammaSD: 93
Range: 8577–9132		22
 Annual posthospitalisation costs for mRS 3–513 604GammaSD: 253
Range: 12 861–14379		22
Utility 
 mRS 0–20.76BetaSD: 0.022
Range: 0.69–0.82		23
 mRS 3–50.21BetaSD: 0.015
Range: 0.17–0.26		23
 mRS 60Beta23
 Recurrent stroke0.20BetaSD: 0.017
Range: 0.16–0.26		23

  • CNY, Chinese yuan renminbi; mRS, modified Rankin Score; MT, mechanical thrombectomy; RR, relative risk.