The frequency of events, corresponding incidence rates and HRs for colorectal cancer events after excluding participants diagnosed with colorectal cancer but no treatment history confirmed
| Proteinuria category | |||
| No (n=2 433 494) | Trace (n=230 931) | Positive (n=78 183) | |
| No. of colorectal cancer events | 6966 | 649 | 312 |
| Incidence rate (per 10 000 person-years) | 8.7 (8.5 to 8.9) | 9.3 (8.6 to 10.1) | 12.5 (11.2 to 14.0) |
| Model 1 (unadjusted) | 1 (reference) | 1.19 (1.10 to 1.29) | 1.52 (1.36 to 1.70) |
| Model 2 | 1 (reference) | 1.24 (1.14 to 1.34) | 1.40 (1.25 to 1.57) |
| Model 3 | 1 (reference) | 1.20 (1.10 to 1.30) | 1.26 (1.12 to 1.41) |
We excluded 2688 participants diagnosed with colorectal cancer but no treatment history for colorectal cancer confirmed. The incidence rate was per 10 000 person-years. Unadjusted and adjusted HRs (95% CIs) associated with the proteinuria group are shown. Model 1 is unadjusted. Model 2 includes adjustment for age and sex. Model 3 includes adjustment for age, sex, obesity, hypertension, diabetes mellitus, dyslipidaemia, cigarette smoking, alcohol consumption and physical inactivity.