Demographic and clinical characteristics of subjects included in the cohort
| WHO ordinal scale <6 (N=267) | WHO ordinal scale 6–9 (N=62) | P value | ||
| Mean (±SD) | ||||
| Age, years | 55.9 (17.8) | 62.9 (13.4) | <0.001 | |
| qSOFA | 0.288 (0.478) | 0.581 (0.560) | <0.001 | |
| Oxygen saturation, % | 95.9 (3.38) | 93.4 (4.56) | <0.001 | |
| C reactive protein, mg/dL | 4.60 (7.78) | 11.7 (10.1) | <0.001 | |
| NLR | 5.69 (5.10) | 9.92 (11.2) | 0.005 | |
| BMI | 31.7 (7.44) | 33.9 (8.93) | 0.068 | |
| D-dimer, ɥg/mL | 2.10 (8.13) | 3.35 (16.6) | 0.564 | |
| Categorised LDH | LDH, ULN | 180 (67.4) | 18 (29.0) | <0.001 |
| 1–2× ULN | 76 (28.5) | 30 (48.4) | ||
| >2× ULN | 11 (4.1) | 14 (22.6) | ||
| N (%) | ||||
| Discharge status | Death | 4 (1.5) | 20 (32.3) | <0.001 |
| Alive | 263 (98.5) | 42 (67.7) | ||
| Code status | Regular | 244 (91.4) | 46 (74.2) | <0.001 |
| Do Not Intubate | 18 (6.7) | 6 (9.7) | ||
| Comfort care | 5 (1.9) | 10 (16.1) | ||
| Sex | Male | 154 (57.7) | 41 (66.1) | 0.282 |
| Female | 113 (42.3) | 21 (33.9) | ||
| Campus | Galveston | 150 (57.3) | 23 (44.2) | – |
| Angleton | 20 (7.6) | 4 (7.7) | ||
| League City | 40 (15.3) | 15 (28.8) | ||
| Clear Lake | 47 (17.9) | 8 (15.4) | ||
| Non-UTMB transfer | 4 (1.5) | 2 (3.8) | ||
| Comorbidities | Cardiovascular | 161 (51.5) | 35 (67.3) | – |
| Diabetes mellitus | 85 (32.4) | 20 (38.5) | ||
| Pulmonary | 55 (21.0) | 6 (11.5) | ||
| Renal | 34 (13.0) | 5 (9.6) | ||
| Liver | 22 (8.4) | 8 (15.4) | ||
| HIV | 2 (0.8) | 2 (3.8) | ||
| Malignancy on chemotherapy | 3 (1.1) | 1 (1.9) | ||
| Solid organ transplant | 6 (2.3) | 1 (1.9) | ||
| Dementia | 11 (4.2) | 2 (3.8) | ||
| Other | 35 (13.4) | 5 (9.6) | ||
| No known medical conditions | 34 (13.0) | 6 (11.5) | ||
*One subject (0.4%) with ordinal scale <6 lacked information on this variable.
BMI, body mass index; LDH, lactate dehydrogenase; NLR, neutrophil to lymphocyte ratio; qSOFA, Quick Sequential Organ Failure Assessment; ULN, upper limit of normal; UTMB, University of Texas Medical Branch.