Table 3

Secondary outcome measures

Phase A
MotherChild
Maternal Outcome Score (MOS)
Caesarean delivery
Pre-eclampsia, eclampsia, HELPP and PIH
Maternal mortality
Postpartum haemorrhage
Thrombosis
Each separate maternal component of GOS
Neonatal Outcome Score (NOS)
IRDS requiring oxygen therapy
Stillbirth and neonatal death
Preterm birth
Shoulder dystocia
Instrumental delivery
Caesarean delivery
Neonatal hypoglycaemia <2.6 mmoL/L
Neonatal jaundice needing phototherapy
NICU admission
Apgar score as a variable
Apgar score <7 at 5 min
Congenital anomaly
Each separate neonatal component of GOS
Phase B and C
MotherChild
Hypertension development
Thrombotic and CVD events
Development of chronic disease
Gonadal and gender development
Puberty and maturation
Educational and intellectual development
Development of chronic disease
  • CVD, Cardiovascular disease; GDM, gestational diabetes mellitus; GOS, GDM Outcome Score; HELLP, Hemolysis Elevated Liver enzymes and Low Platelets; IRDS, Infant Respiratory Distress Syndrome; NICU, neonatal intensive care unit; PIH, Pregnancy induced hypertension.