Baseline characteristics
| Variable | LMICs (N=1104) N (%) | HICs (N=556) N (%) | Total (N=1660) N (%) | P value | |
| Age (years), median (range) | 5.00 (2.0–10.0) | 7.00 (3.0–13.0) | 6.00 (3.0–11.0) | <0.001 | |
| Sex | Female | 469 (42.5) | 230 (41.4) | 699 (42.1) | 0.66 |
| Male | 631 (57.2) | 324 (58.3) | 955 (57.5) | ||
| Missing | 4 (0.4) | 2 (0.4) | 6 (0.4) | ||
| Weight (kg), median (range) | 18.0 (13.0–29.0) | 27.1 (16.8–49.1) | 20.0 (14.0–35.0) | <0.001 | |
| ASA grade | (1a) Normal healthy patient | 344 (31.2) | 101 (18.2) | 445 (26.8) | <0.001 |
| (2a) Patient with mild systemic disease | 423 (38.3) | 206 (37.1) | 629 (37.9) | ||
| (3a) Patient with severe systemic disease | 149 (13.5) | 220 (39.6) | 369 (22.2) | ||
| (4a) Patient with severe systemic disease that is a constant threat to life | 34 (3.1) | 25 (4.5) | 59 (3.6) | ||
| (5a) Moribund patient who is not expected to survive without the operation | 8 (0.7) | 0 (0.0) | 8 (0.5) | ||
| Missing | 146 (13.2) | 4 (0.7) | 150 (9.0) | ||
| Tumour type | Non-Hodgkin’s lymphoma | 89 (8.1) | 29 (5.2) | 118 (7.1) | <0.001 |
| Acute lymphoblastic leukaemia | 380 (34.4) | 234 (42.1) | 614 (37.0) | ||
| Ewing sarcoma | 32 (2.9) | 31 (5.6) | 63 (3.8) | ||
| Glioma | 73 (6.6) | 69 (12.4) | 142 (8.6) | ||
| Hodgkin lymphoma | 63 (5.7) | 38 (6.8) | 101 (6.1) | ||
| Medulloblastoma | 57 (5.2) | 31 (5.6) | 88 (5.3) | ||
| Neuroblastoma | 80 (7.2) | 48 (8.6) | 128 (7.7) | ||
| Osteosarcoma | 45 (4.1) | 25 (4.5) | 70 (4.2) | ||
| Retinoblastoma | 87 (7.9) | 4 (0.7) | 91 (5.5) | ||
| Rhabdomyosarcoma | 61 (5.5) | 25 (4.5) | 86 (5.2) | ||
| Wilms tumour | 137 (12.4) | 22 (4.0) | 159 (9.6) | ||
| Was patient tested for COVID-19? | No | 631 (57.2) | 148 (26.6) | 779 (46.9) | <0.001 |
| Yes | 367 (33.2) | 366 (65.8) | 733 (44.2) | ||
| Missing | 106 (9.6) | 42 (7.6) | 148 (8.9) | ||
| Was patient diagnosed with COVID-19? | No | 943 (85.4) | 519 (93.3) | 1462 (88.1) | 0.004 |
| Not applicable (no anti-cancer treatment given post March 11th 2020) | 11 (1.0) | 3 (0.) | 14 (0.8) | ||
| Proven with laboratory test or CT Thorax | 31 (2.8) | 6 (1.1) | 38 (2.2) | ||
| Probable—clinically suspected | 5 (0.54) | 3 (0.5) | 8 (0.5) | ||
| Unknown | 74 (6.7) | 19 (3.4) | 93 (5.6) | ||
| Missing | 40 (3.6) | 6 (1.1) | 46 (2.8) |
ASA, American Society of Anesthesiologists; HICs, high-income countries; LMICs, low-income and middle-income countries.