Table 1

First-ever total prostate-specific antigen (PSA) median and IQR reported for age category and race group between 2006 and 2016 in the Gauteng Province, South Africa

CategoryMedian (IQR)
µg/L
%≥75th Percentile%≥4 µg/L%<10 µg/L
(Low risk)
%10–19.9 µg/L
(Intermediate risk)
%≥20 µg/L
(High risk)
P value*
Overall 0.9 (0-5–1.8) 25.2% 11.7% 227 629 (95.0%) 5439 (2.3%) 6438 (2.7%)
Age category
 30–390.7 (0.4–1.0)25.7%1.7%19 481 (99.6%)50 (0.3%)26 (0.1%)
 40–490.7 (0.4–1.1)25.1%2.3%57 891 (99.4%)195 (0.3%)129 (0.2%)≤0.05
 50–590.8 (0.5–1.5)26.0%7.5%71 842 (97.4%)1009 (1.4%)883 (1.2%)≤0.05
 60–691.3 (0.7–2.9)25.0%18.5%51 002 (92.3%)1946 (3.5%)2330 (4.2%)≤0.05
 ≥702.3 (1.0–6.4)25.0%35.5%22 644 (82.0%)2070 (7.5%)2885 (10.5%)≤0.05
 Unknown1.0 (0.6–2.1)25.5%14.8%4769 (93.1%)169 (3.3%)186 (3.6%)≤0.05
Race group
 Indian/Asian0.9 (0.5–1.8)21.8%10.7%4 016 (96.3%)86 (2.1%)67 (1.6%)
 Black African0.9 (0.5–1.8)25.8%11.6%177 049 (96.3%)4 271 (2.1%)5262 (1.6%)0.1527
 Multiracial0.9 (0.5–1.9)25.1%12.6%8183 (94.9%)208 (2.4%)232 (2.7%)≤0.05
 White1.0 (0.5–2.0)22.7%12.5%15 965 (95.5%)380 (2.1%)316 (2.4%)≤0.05
 Unknown0.9 (0.5–1.8)24.7%11.2%22 416 (95.8%)494 (2.3%)561 (1.9%)0.2374
  • The proportion of men with a first-ever total PSA test ≥75th percentile, ≥4,<10 (low risk), 10–19.9 (intermediate-risk) and ≥20 µg/L (high risk) are also reported for age category and race group. The p value for the Dunn’s test for multiple pairwise comparisons was reported (compared with the first category).

  • *For each age category and race group, the Dunn’s test for multiple pairwise comparisons was performed and the p-value reported when compared with the first category.