Outcomes (unit) (intervention;control)* | Intervention (myo-inositol) Mean (SD) | Control (placebo) mean (SD) | MD (95% CI) |
OGTT fasting (mmol/L) (81; 81) | 4.5 (0.5) | 4.6 (0.4) | −0.0 (−0.2 to 0.1) |
OGTT 2 hours (mmol/L) (80; 81) | 6.1 (2) | 6.0 (1.3) | 0.0 (−0.5 to 0.6) |
HOMA-IR (50; 62) | 2.13 (1.32) | 2.8 (2.05) | −0.6 (−1.2 to 0.0) |
Insulin (mlU/L) (53; 63) | 10.63 (6.11) | 13.72 (8.89) | −2.69 (−5.26 to −0.18) |
Leptin (μg/L) (53; 63) | 42.7 (21.6) | 38.3 (17.1) | 4.4 (−2.7 to 11.4) |
Adiponectin (mg/L) (53; 63) | 6.6 (3.5) | 6.1 (3.8) | 0.5 (−0.9 to 1.8) |
Urinary inositol (mg/L) (53; 65) | 265.7 (209.7) | 194.7 (118.7) | 70.76 (11.2 to 130.8) |
c-peptide (μg/L) (53; 63) | 1538.5 (679.6) | 1804.3 (807.8) | −253.6 (−522.7 to 10.4) |
c-peptide in cord blood (μg/L) (10; 6) | 457 (268.04) | 535 (296.02) | −101.74 (−358.17 to 202.17) |
*Number of women in the intervention and control group, respectively.
†Values in bold specifically described within secondary outcomes results.
HOMA-IR, homoeostatic model assessment-insulin resistance; MD, mean difference; OGTT, oral glucose tolerance test.