Baseline n (%)* | 3 months of follow-up n (%)* | 6 months of follow-up n (%)* | |||||||
Control | Intervention | Total | Control | Intervention | Total | Control | Intervention | Total | |
TB treatment status† | |||||||||
Successful‡ | 204 (70.1) | 192 (67.8) | 396 (69.0) | ||||||
Not Successful | 87 (29.9) | 91 (32.16) | 178 (31.01) | ||||||
Cured†,§ | |||||||||
Yes | 83 (39.9) | 85 (43.6) | 168 (41.7) | ||||||
No | 125 (60.1) | 110 (56.4) | 235 (58.3) | ||||||
Continuous smoking abstinence¶ | |||||||||
Yes | 27 (16.3) | 20 (11.2) | 47 (13.6) | 12 (7.2) | 10 (5.6) | 22 (6.4) | |||
No | 139 (83.7) | 159 (88.8) | 298 (86.4) | 154 (92.8) | 169 (94.4) | 323 (93.6) | |||
Harmful/hazardous drinkers** (N) | 188†† | 206†† | 394†† | 141†† | 130†† | 271†† | 112†† | 127†† | 239†† |
AUDIT score, mean (SD) | 12.76 (3.42) | 13.12 (3.47) | 12.94 (3.45) | 8.28 (6.18) | 8.84 (5.38) | 8.55 (5.81) | 8.79 (6.66) | 8.70 (5.83) | 8.74 (6.22) |
Difference from baseline, mean (SD) | −4.61 (6.26) | −4.07 (5.33) | −4.35 (5.83) | −4.25 (6.56) | −4.17 (6.61) | −4.21 (6.57) | |||
HIV-positive patients | 163†† (56.2) | 142†† (50.2) | 305†† (53.2) | 122†† | 83†† | 205†† | 100†† | 83†† | 183†† |
Taking ART medication if HIV positive‡‡ | 139 (85.3) | 115 (81.0) | 254 (83.3) | 91 (74.6) | 58 (69.9) | 149 (72.7) | 80 (80.0) | 74 (89.2) | 154 (84.2) |
ART medication adherence¶ | |||||||||
Optimal adherence | 101 (99.0) | 64 (98.5) | 165 (98.8) | 75 (97.4) | 64 (97.0) | 139 (97.2) | |||
Suboptimal adherence | 1 (1.0) | 1 (1.54) | 2 (1.2) | 2 (2.6) | 2 (3.0) | 4 (2.8) | |||
TB medication adherence | |||||||||
Optimal adherence | 181 (92.3) | 138 (90.8) | 319 (91.7) | 61 (89.7) | 59 (90.8) | 120 (90.2) | |||
Suboptimal adherence | 15 (7.6) | 14 (9.2) | 29 (8.3) | 7 (10.3) | 6 (9.2) | 13 (9.8) |
*Frequencies and (percentages) are presented unless otherwise stated.
†Only assessed at 6-months.
‡Primary outcome: this is a binary variable defined as either successful treatment (cured or treatment completed) or failed treatment, death, acquired drug resistance, loss to follow-up or treatment interrupted for more than 2 months, or outcome not evaluated/unknown.
§Based on having a cured treatment outcome among those who were bacteriologically positive at baseline.
¶Assessed at 3 and 6 months; this table refers to cigarette smokers only (other forms of tobacco smoking are excluded).
**Hazardous/harmful drinkers who are not alcohol dependent=AUDIT score of ≥8 for men or ≥7 for women but <20; *! Important distinction at baseline for eligibility purposes.
††Denominator for the mean (SD) or denominator for %.
‡‡Information on HIV positivity was obtained from information from TB records combined with patient self-report at baseline. True HIV-positivity rates may have been higher.
ART, antiretroviral therapy; AUDIT, Alcohol Use Disorders Identification Test; TB, tuberculosis.