Table 5

Association between recruitment rate (number of participants/centre/month) and trial characteristics

Characteristic (n=365)		n	Median	IQR	P value
Setting	Hospital	212	0.90	0.4–2.29	0.009*†
	General practice	51	0.71	0.32–1.18
	Mixed	56	1.01	0.47–2.64
	Community	29	2.44	0.62–6.41
	Other	17	1.89	0.76–11.7
Arms	2	278	1.10	0.41–2.76	0.935‡
	3	55	0.85	0.45–2.1
	4	22	1.04	0.57–1.91
	>4	10	0.85	0.42–8.85
Control type	Placebo	85	0.84	0.38–1.93	0.145§
Control type	Active	280	1.03	0.43–3.22
Original target recruitment	≤200	41	1.18	0.47–2.65	0.008‡
	201–400	93	0.78	0.36–2.01
	401–600	84	0.84	0.43–1.96
	601–800	40	1.13	0.46–2.88
	>800	105	1.49	0.55–4.72
Final target recruitment	≤200	45	0.89	0.27–2.55	<0.001‡
	201–400	103	0.76	0.34–1.96
	401–600	83	0.86	0.44–2.26
	601–800	41	1.17	0.57–4.23
	>800	93	1.66	0.58–5.17
Total recruitment	≤200	63	0.50	0.17–1.6	<0.001‡
	201–400	90	0.78	0.37–2.07
	401–600	81	1.15	0.49–2.41
	601–800	39	1.03	0.57–3.85
	>800	92	1.96	0.68–6.23
Timing of final follow-up	≤1 month	19	1.29	0.42–2.26	0.054‡
	1< months ≤6	82	1.14	0.38–4.14
	6< months ≤18	170	0.98	0.46–2.33
	>18 months	85	0.71	0.36–2.02