Crude rates of renal outcomes among eligible adults between 1 January 2008 and 31 December 2012 with no evidence of prior diuretic use, overall and stratified by incident use of diuretics
| End-stage renal disease events per 100 person-years | Composite renal outcome* events per 100 person-years | |
| Overall | 0.42 (0.39–0.45) | 1.35 (1.30–1.41) |
| Loop diuretic use | ||
| No incident use | 0.30 (0.28–0.33) | 1.06 (1.02–1.12) |
| Incident use | 4.92 (4.34–5.59) | 12.85 (11.81–13.98) |
| Thiazide diuretic use | ||
| No incident use | 0.43 (0.40–0.46) | 1.29 (1.24–1.35) |
| Incident use | 0.30 (0.20–0.46) | 2.68 (2.33–3.08) |
*End-stage renal disease, eGFR <15 mL/min/1.73 m2 and/or ≥50% reduction in eGFR.
eGFR, estimated glomerular filtration rate.