Symptom characteristics and ORs of CoVHORT participants using a logistic regression model adjusted for case status, age, sex, ethnicity, BMI and smoking status
| Reported symptoms at study entry | COVID-19 positive* n=1155 n (%) | Untested participants† n=288 n (%) | COVID-19 negative‡ n=930 n (%) | Positive versus untested OR (95% CI) | Positive versus negative OR (95% CI) |
| Fatigue | 957 (82.9) | 236 (82.2) | 680 (73.1) | 1.1 (0.7 to 1.5) | 1.81 (1.5 to 2.3) |
| Headache | 861 (74.6) | 167 (58.2) | 495 (53.2) | 2.1 (1.5 to 2.7) | 2.6 (2.2 to 3.2) |
| Aches and pains or sore muscles | 766 (66.3) | 178 (62.0) | 506 (54.4) | 1.2 (0.9 to 1.6) | 1.7 (1.4 to 2.0) |
| Loss of smell/taste | 725 (62.8) | 67 (23.4) | 119 (12.8) | 6.0 (4.3 to 8.3) | 12.4 (9.8 to 15.7) |
| Cough | 716 (61.9) | 209 (72.8) | 540 (58.1) | 0.7 (0.5 to 0.9) | 1.2 (1.0 to 1.4) |
| Fever | 610 (52.8) | 171 (59.6) | 452 (48.6) | 0.8 (0.6 to 1.0) | 1.2 (1.0 to 1.5) |
| Runny nose/cold-like symptoms | 684 (59.2) | 139 (48.4) | 451 (48.5) | 1.5 (1.1 to 1.9) | 1.6 (1.3 to 1.9) |
| Chills | 563 (48.7) | 132 (46.0) | 339 (36.5) | 1.2 (0.9 to 1.5) | 1.7 (1.4 to 2.0) |
| Sore throat | 543 (47.0) | 161 (56.1) | 507 (54.5) | 0.6 (0.5 to 0.8) | 0.7 (0.6 to 0.9) |
| Difficulty breathing or shortness of breath | 475 (41.1) | 132 (46.0) | 319 (34.3) | 0.8 (0.6 to 1.1) | 1.4 (1.1 to 1.6) |
| Diarrhoea | 348 (30.1) | 71 (24.7) | 162 (17.4) | 1.3 (1.0 to 1.8) | 2.0 (1.6 to 2.5) |
| Nausea | 326 (28.2) | 51 (17.8) | 129 (13.9) | 1.9 (1.3 to 2.7) | 2.5 (1.9 to 3.1) |
| Chest pain or pressure | 362 (31.3) | 88 (30.7) | 246 (26.5) | 1.1 (0.8 to 1.4) | 1.3 (1.1 to 1.6) |
| Bone pain/nerve pain | 212 (18.4) | 20 (7.0) | 66 (7.1) | 2.9 (1.8 to 4.8) | 3.0 (2.2 to 4.0) |
| Vomiting | 92 (8.0) | 13 (4.5) | 44 (4.7) | 1.8 (1.0 to 3.5) | 1.7 (1.1 to 2.4) |
| Other | 101 (8.7) | 17 (5.9) | 32 (3.4) | 1.8 (1.0 to 3.1) | 2.9 (1.9 to 4.3) |
| Rash on skin | 82 (7.1) | 15 (5.2) | 38 (4.1) | 1.5 (0.8 to 2.8) | 1.8 (1.2 to 2.8) |
| Discolouration of fingers/toes | 29 (2.5) | 4 (1.4) | 18 (1.9) | 2.2 (0.6 to 7.2) | 1.3 (0.7 to 2.3) |
| Loss of speech or movement | 12 (1.0) | 1 (0.4) | 7 (0.8) | 2.8 (0.4 to 22.0) | 1.3 (0.5 to 3.4) |
| Conjunctivitis | 26 (2.3) | 11 (3.8) | 28 (3.0) | 0.6 (0.3 to 1.3) | 0.8 (0.5 to 1.4) |
*PCR-positive cases.
†Participants in CoVHORT who do not have a laboratory-confirmed result.
‡PCR or antibody negative.
BMI, body mass index.