Table 3

Comparison of polypharmacy in clinic-based practices and hospital-based practices among patients with complex multimorbidity* (N=492)

OutcomeUnadjustedP valueAdjusted†P value
Relative risk (95% CI)Relative risk (95% CI)
Polypharmacy‡0.55 (0.36 to 0.83)0.0050.53 (0.35 to 0.82)0.004
Number of regular medications
 Total0.85 (0.74 to 0.97)0.0200.87 (0.78 to 0.97)0.014
 Prescription medications0.85 (0.73 to 0.98)0.0290.86 (0.77 to 0.97)0.014
 Over-the-counter medications0.87 (0.60 to 1.27)0.4750.90 (0.63 to 1.32)0.608
  • *Reference group: hospitals; generalised linear mixed model; random effect on facility.

  • †Adjusted for age, sex, years of education, annual household income, number of chronic conditions, eye and adnexa, digestive, and respiratory diseases, hospitalisation in past 6 months, and municipality population size.

  • ‡Use of ≥5 concurrent medications.