Diagnosis type on initial opioid prescriptions dispensed to Rhode Island residents, 1 April 2019 to 31 March 2020*
| Diagnosis type | Overall | Subsequent chronic prescription opioid use | |
| Yes | No | ||
| N=87 055 n (%) | N=3199 n (%) | N=83 856 n (%) | |
| Unknown | 31 574 (36.27) | 894 (27.95) | 30 680 (36.59) |
| Diseases of the musculoskeletal system and connective tissue | 15 525 (17.83) | 1157 (36.17) | 14 368 (17.13) |
| Diseases of the nervous system | 8377 (9.62) | 601 (18.79) | 7776 (9.27) |
| Diseases of the digestive system | 7552 (8.67) | 34 (1.06) | 7518 (8.97) |
| Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified | 7133 (8.19) | 158 (4.94) | 6975 (8.32) |
| Factors influencing health status and contact with health services | 3833 (4.40) | 63 (1.97) | 3770 (4.50) |
| Injury, poisoning and certain other consequences of external causes | 3290 (3.78) | 55 (1.72) | 3235 (3.86) |
| Diseases of the genitourinary system | 2974 (3.42) | 12 (0.38) | 2962 (3.53) |
| Neoplasms | 1960 (2.25) | 148 (4.63) | 1812 (2.16) |
| Pregnancy, childbirth and the puerperium | 1246 (1.43) | <5 | 1244 (1.48) |
| Diseases of the respiratory system | 811 (0.93) | 12 (0.38) | 799 (0.95) |
| Diseases of the skin and subcutaneous tissue | 756 (0.87) | 15 (0.47) | 741 (0.88) |
| Diseases of the circulatory system | 479 (0.55) | 16 (0.50) | 463 (0.55) |
| Certain infectious and parasitic diseases | 416 (0.48) | 5 (0.16) | 411 (0.49) |
| Diseases of the eye and adnexa | 277 (0.32) | <5 | 275 (0.33) |
| Mental and behavioural disorders | 272 (0.31) | 9 (0.28) | 263 (0.31) |
| Endocrine, nutritional and metabolic diseases | 267 (0.31) | 6 (0.19) | 261 (0.31) |
| Congenital malformations, deformations and chromosomal abnormalities | 145 (0.17) | 5 (0.16) | 140 (0.17) |
| Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism | 85 (0.10) | <5 | 81 (0.10) |
| External causes of morbidity and mortality | 82 (0.09) | <5 | 81 (0.09) |
| Certain conditions originating in the perinatal period | <5 | 0 (0.00) | <5 |
*Initial opioid prescriptions were defined as either the patient’s first opioid prescription or an opioid prescription that started at least 60 days after the patient’s previous opioid prescription ended. For patients with more than one initial opioid prescription during this period, we randomly selected one for inclusion in this analysis.