Patient demographics and study characteristics
| Demographics and study characteristics | No |
| Total no of studies | 110 |
| Total no of participants | 9 799 329 |
| Mean age, year, IQR | 73.0 (50–93.06) |
| Study design | |
| Cross-sectional | 53 (48%) |
| Longitudinal | 43 (39%) |
| Case-control | 14 (13%) |
| Country | |
| USA | 30 (27%) |
| Japan | 6 (5%) |
| UK | 6 (5%) |
| China | 6 (5%) |
| Australia | 5 (4.5%) |
| France | 5 (4.5%) |
| Germany | 5 (4.5%) |
| Singapore | 5 (4.5%) |
| Ireland | 3 (3%) |
| Canada | 3 (3%) |
| Spain | 2 (2%) |
| Taiwan | 2 (2%) |
| Sweden | 1 (<1%) |
| Nordic Countries | 1 (<1%) |
| New Zealand | 1 (<1%) |
| Switzerland | 1 (<1%) |
| Netherland | 1 (<1%) |
| Others | 27 (25%) |