Sensitivity and specificity (as percent), with 95% CIs (in parentheses) of clinical signs of jaundice in neonates aged 1–20 days as assessed by primary healthcare workers for detecting levels of hyperbilirubinaemia
| Sensitivity | Specificity | |||||||||||
| Dhaka | Delhi | Chandigarh | Durban | Kumasi | La Paz | Dhaka | Delhi | Chandigarh | Durban | Kumasi | La Paz | |
| Serum bilirubin > 260 mmol/l (15 mg/dl) | ||||||||||||
| (n=35)* | (n=61) | (n=38) | (n=18) | (n=17) | (n=103) | (n=41) | (n=54) | (n=294) | (n=103) | (n=46) | (n=78) | |
| Deep jaundice of the head | 51 (34 to 69) | 90 (80 to 96) | 32 (18 to 49) | 56 (31 to 78) | 75 (65 to 83) | 66 (49 to 80) | 48 (34 to 62) | 89 (85 to 92) | 80 (71 to 87) | 49 (37 to 60) | ||
| Deep jaundice of the runk | 31(17 to 49) | 66 (52 to 77) | 26 (13 to 43) | 47 (21 to 73) | 31 (22 to 41) | 78 (62 to 89) | 81 (69 to 91) | 96 (93 to 98) | 82 (72 to 90) | 83 (73 to 91) | ||
| Any jaundice of the distal extremities | 66 (48 to 81) | 64 (51 to 76) | 55 (38 to 71) | 56 (31 to 78) | 88 (64 to 99) | 42 (32 to 52) | 66 (49 to 80) | 80 (66 to 89) | 89 (85 to 92) | 56 (46 to 66) | 76 (61 to 87) | 71 (59 to 80) |
| Any jaundice of the distal extremities OR deep jaundice of the trunk | 66 (48 to 81) | 77 (65 to 87) | 58 (41 to 74) | 67 (41 to 87) | 44 (34 to 54) | 66 (49 to 80) | 72 (58 to 84) | 88 (84 to 92) | 49 (39 to 59) | 69 (58 to 79) | ||
| Any jaundice of the distal extremities OR deep jaundice of the head or trunk | 69 (51 to 83) | 93 (84 to 98) | 58 (41 to 74) | 83 (59 to 96) | 80 (71 to 87) | 63 (47 to 78) | 48 (34 to 62) | 84 (79 to 88) | 48 (38 to 58) | 46 (35 to 58) | ||
| Serum bilirubin > 340 mmol/l (20 mg/dl) | ||||||||||||
| (n=14)† | (n=25) | (n=9) | (n=2)‡ | (n=7) | (n=35) | (n=62) | (n=90) | (n=323) | (n=119) | (n=56) | (n=146) | |
| Deep jaundice of the head | 79 (49 to 95) | 96 (80 to 100) | 67 (30 to 93) | 94 (81 to 99) | 66 (53 to 78) | 34 (25 to 45) | 88 (84 to 92) | 76 (67 to 83) | 42 (34 to 51) | |||
| Deep jaundice of the trunk | 64 (35 to 87) | 76 (55 to 91) | 44 (14 to 79) | 46 (29 to 63) | 82 (70 to 91) | 66 (55 to 75) | 94 (91 to 97) | 77 (68 to 85) | 80 (73 to 86) | |||
| Any jaundice of the distal extremities | 93 (66 to 100) | 80 (59 to 93) | 89 (52 to 100) | 100 (59 to 100) | 57 (39 to 74) | 61 (48 to 73) | 67 (56 to 76) | 86 (81 to 89) | 55 (45 to 64) | 66 (52 to 78) | 68 (60 to 76) | |
| Any jaundice of the distal extremities OR deep jaundice of the head or trunk | 93 (66 to 100) | 88 (69 to 97) | 89 (52 to 100) | 60 (42 to 76) | 61 (48 to 73) | 56 (45 to 66) | 85 (80 to 89) | 46 (37 to 56) | 67 (59 to 75) | |||
| Any jaundice of the distal extremities OR deep jaundice of the head or trunk | 93 (66 to 100) | 100 (86 to 100) | 89 (52 to 100) | 97 (85 to 100) | 58 (45 to 70) | 33 (24 to This study had several limitations. We) | 81 (76 to 85) | 44 (35 to 53) | 38 (30 to 47) | |||
*Numbers apply to serum bilirubin >260 mmol/L (15 mg/dL) for sites.
†Numbers apply to serum bilirubin >340 mmol/L (20 mg/dL) for sites.
‡Both cases were found to have deep jaundice of the face, and one also had jaundice of palms and soles.