Table 1

Comparison the diagnostic value among conventional, Doppler and contrast-enhanced US

Diagnostic toolSensitivitySpecificityPLRNLRDORAUC
US0.91 (0.87 to 0.94)0.87 (0.82 to 0.91)6.87 (4.98 to 9.49)0.10 (0.07 to 0.15)57.52 (36.64 to 90.28)0.95 (0.93 to 0.97)
Doppler US0.93 (0.91 to 0.95)0.85 (0.80 to 0.89)6.10 (4.59 to 8.11)0.08 (0.06 to 0.11)61.76 (39.99 to 95.37)0.96 (0.94 to 0.97)
CEUS0.97 (0.92 to 0.99)0.92 (0.85 to 0.95)11.47 (6.52 to 20.17)0.03 (0.01 to 0.09)152.11 (77.77 to 297.51)0.99 (0.97 to 0.99)
US vs Doppler US0.98 (0.94 to 1.02)/0.3361.02 (0.95 to 1.10)/0.5411.13 (0.73 to 1.73)/0.5881.25 (0.77 to 2.03)/0.3690.93 (0.50 to 1.74)/0.8240.99 (0.96 to 1.02)/0.435
US vs CEUS0.94 (0.89 to 0.99)/0.0190.95 (0.88 to 1.02)/0.1510.60 (0.31 to 1.15)/0.1223.33 (1.04 to 10.66)/0.0420.38 (0.17 to 0.85)/0.0180.96 (0.94 to 0.98)/0.002
Doppler US vs CEUS0.96 (0.92 to 1.00)/0.0520.92 (0.86 to 1.00)/0.0440.53 (0.28 to 1.00)/0.0502.67 (0.85 to 8.34)/0.0920.41 (0.18 to 0.90)/0.0270.97 (0.95 to 0.99)/0.005
  • AUC, area under the curve ; CEUS, contrast-enhanced US ; DOR, diganostic OR; NLR, negative likelihood ratio; PLR, positive likelihood ratio; US, ultrasonography.