Biomass analysis results—two-sample t-test on the log10 change
| Two sample t-test on log10 change (CHL-PLA) | N TOT | N CHL | N PLA | Mean difference (SE)* | 95% CI | T value | P value |
| All participants with available data | |||||||
| Oral wash samples | 40 | 20 | 20 | −0.103 (0.23) | −0.59 to 0.38 | −0.44 | 0.665 |
| Sputum samples | |||||||
| No imputation | 27 | 15 | 12 | 0.80 (0.46) | −0.15 to 1.75 | 1.73 | 0.096 |
| Imputation† | 35 | 19 | 16 | 0.70 (0.39) | −0.08 to 1.47 | 1.76 | 0.078 |
| Excluding antibiotic use during study | |||||||
| Oral wash samples | 32 | 17 | 15 | −0.07 (0.29) | −0.65 to 0.51 | −0.25 | 0.808 |
| Sputum samples | |||||||
| No imputation | 23 | 14 | 9 | 1.06 (0.53) | −0.05 to 2.17 | 1.99 | 0.060 |
| Imputation† | 28 | 16 | 12 | 0.98 (0.47) | 0.06 to 1.89 | 2.09 | 0.036 |
*Chlorhexidine group change in biomass minus placebo group.
†Imputation refers to the use of multiple imputation techniques to impute the 11 missing sputum weights.
CHL, chlorhexidine; PLA, placebo; TOT, total.