Table 5

Clinical features, patterns of treatment and clinical outcomes of water intoxication

% (no/total data available)AllMild hyponatraemia (130–134 mmol/L)Moderate hyponatraemia (125–129 mmol/L)Severe hyponatraemia (<125 mmol/L)
Clinical features
 Not reported4.5% (11/223)10% (1/10)15% (4/27)3.2% (6/186)
 No symptoms2.7% (6/223)40% (4/10)4% (1/27)0.5% (1/186)
 Mild4.9% (10/223)10% (1/10)7% (2/27)3.8% (7/186)
 Moderate34.5 (77/223)40% (4/10)37% (10/27)33.9% (63/186)
 Severe53.4% (119/223)0% (0/10)37% (10/27)58.6% (109/186)
Onset of clinical features
 Not known30% (67/223)0% (0/10)37% (10/27)30.7% (57/186)
 No clinical features reported/asymptomatic3% (6/223)40% (4/10)4% (1/27)0.5% (1/186)
 Acute (<48 hours)41% (92/223)30% (3/10)41% (11/27)41.9% (78/186)
 Chronic (>48 hours)26% (58/223)40% (4/10)18% (5/27)26.9% (50/186)
Treatment types
 Not reported13% (28/223)30% (3/10)22% (6/27)10% (19/186)
 Supportive Care41% (92/223)50% (5/10)48% (13/27)40% (74/186)
 Isotonic saline18% (41/223)10% (1/10)15% (4/27)19% (36/186)
 Hypertonic (3%) saline28% (62/223)10% (1/10)15% (4/27)31% (57/186)
Treatment complications
 None90% (200/223)100% (10/10)96% 26/27)88% (164/186)
 Rhabdomyolysis7% (16/223)0% (0/10)4% (1/27)8% (15/186)
 Osmotic demyelination3% (7/223)0% (0/10)0% (0/27)4% (7/186)
Outcomes
 Not reported9% (19/223)40% (4/10)18.5% (5/27)5% (10/186)
 Recovered (partial/complete)78% (175/223)60% (6/10)77.8% (21/27)80% (148/186)
 Death13% (29/223)0% (0/10)3.7% (1/27)15% (28/186)