Table 4

Coefficient for cirrhosis under different multiple regression models

ModelCirrhosis b (95% CI)b
Univariable regression on cirrhosis−0.49 (−0.67 to −0.32)
Model 1: Adjusted for age, pretreatment K+, log creatinine, active cancer, beta-blocker use, and cotreatments (n=463)*−0.48 (−0.64 to −0.31)+2.8%†
Model 2: Adjusted for Model 1 covariates and the pretreatment pH levels (n=463)‡−0.48 (−0.64 to −0.32)−0.3%§
Model 3: Sensitivity analysis, Model 1 covariates excluding patients who received repeat insulin-glucose treatment (n=370)−0.42 (−0.61 to −0.23)+12.1%§
Model 4: Sensitivity analysis, Model 2 covariates excluding patients who received repeat insulin-glucose treatment (n=370)−0.44 (−0.63 to −0.25)+8.8%¶
  • *Intravenous furosemide excluded from cotreatment list as it was balanced in both groups and not statistically significant in the model.

  • †Percent change in b coefficient compared with univariable regression.

  • ‡Number of missing pretreatment pH observations imputed was 69 (14.9%).

  • §Percent change in b coefficient compared with Model 1.

  • ¶Percent change in b coefficient compared with Model 2.