Table 3

β (95% CIs) and ORs (95% CIs) of dietary intakes of antioxidant vitamins and homocysteine levels among the middle-aged and older hypertensive participants

tHcyQ1Q2Q3Q4Pfor trend
Vitamin C (mg/day)<91.291.2–153.5153.6–240.9≥240.9
 Cases (%)132 (36.1)122 (33.3)104 (28.4)111 (30.2)
 Crude model−0.037 (−0.063, –0.011)Ref.0.89 (0.65, 1.20)0.70 (0.52, 0.96)0.77 (0.56, 1.05)0.071
 Model I−0.031 (−0.055, –0.006)Ref.0.92 (0.66, 1.27)0.64 (0.46, 0.90)0.55 (0.34, 0.89)0.048
 Model II−0.050 (−0.084, –0.016)Ref.0.82 (0.57, 1.16)0.49 (0.33, 0.74)0.40 (0.22, 0.74)0.001
Vitamin E (mg/day)<19.319.3–25.025.1–31.9≥31.9
 Cases (%)122 (33.6)126 (34.2)113 (30.9)108 (29.3)
 Crude model−0.035 (−0.084, 0.014)Ref.1.03 (0.76, 1.40)0.88 (0.65, 1.20)0.82 (0.60, 1.12)0.139
 Model I−0.007 (−0.053, 0.039)Ref.1.10 (0.79, 1.53)0.96 (0.69, 1.34)0.95 (0.68, 1.33)0.618
 Model II−0.009 (−0.055, 0.036)Ref.1.12 (0.80, 1.57)0.95 (0.68, 1.33)0.91 (0.65, 1.28)0.412
Carotenes (mg/day)<1.781.78–3.303.31–5.61≥5.61
 Cases (%)118 (32.7)136 (37.0)99 (26.8)116 (31.6)
 Crude model−0.024 (−0.045, –0.003)Ref.1.21 (0.89, 1.64)0.76 (0.55, 1.04)0.95 (0.70, 1.30)0.315
 Model I−0.022 (−0.042, –0.003)Ref.1.22 (0.88, 1.69)0.72 (0.51, 1.01)0.93 (0.67, 1.30)0.254
 Model II−0.022 (−0.052, 0.009)Ref.1.18 (0.84, 1.68)0.68 (0.46, 1.02)0.76 (0.43, 1.35)0.159
Retinol (µg/day)<78.078.0–138.3138.4–283.6≥283.6
 Cases (%)147 (40.2)133 (36.3)91 (24.9)98 (26.7)
 Crude model−0.030 (−0.046, –0.015)Ref.0.85 (0.63, 1.15)0.49 (0.36, 0.68)0.54 (0.40, 0.74)0.001
 Model I−0.027 (−0.041, –0.012)Ref.0.84 (0.61, 1.16)0.50 (0.35, 0.70)0.55 (0.40, 0.77)0.003
 Model II−0.021 (−0.041, –0.002)Ref.0.90 (0.65, 1.25)0.61 (0.42, 0.86)0.86 (0.56, 1.32)0.951
Lutein (mg/day)<5.225.22–9.489.49–14.82≥14.82
 Cases (%)123 (33.7)120 (32.8)114 (31.1)112 (30.4)
 Crude model−0.028 (−0.053, –0.004)Ref.0.96 (0.71, 1.31)0.89 (0.65, 1.21)0.86 (0.63, 1.17)0.311
 Model I−0.024 (−0.046, –0.001)Ref.0.98 (0.71, 1.37)0.84 (0.61, 1.17)0.87 (0.62, 1.22)0.331
 Model II−0.025 (−0.063, 0.013)Ref.0.92 (0.65, 1.31)0.76 (0.51, 1.14)0.66 (0.37, 1.19)0.138
  • Model I: Adjusted for age, sex (‘male’ as the reference) BMI.

  • Model II: Adjusted for variables in model I and further adjusted for sedentary time (‘<3 hours/day’ as the reference), the intakes of folate, vitamin B6 and vitamin B12, supplement use (‘no’ as the reference) and the history of cardiovascular events (‘no’ as the reference).

  • BMI, body mass index; tHcy, total homocysteine.