Table 2

Univariate Fine and Gray model for baseline characteristics, laboratory parameters and inflammatory biomarkers

VariablesUnivariate analysis
MortalityDischarged alive
SHR95% CIP valueSHR95% CIP value
Age≤401.001.00
41–592.040.90 to 4.660.0890.800.64 to 1.010.057
≥603.511.53 to 8.070.0030.560.42 to 0.73<0.001
GenderMale1.190.64 to 2.190.5820.870.70 to 1.090.228
Blood groupO1.001.00
A0.940.48 to 1.870.8660.890.69 to 1.150.389
B1.130.63 to 2.010.6890.930.75 to 1.180.578
AB2.010.80 to 5.050.1390.660.39 to 1.110.116
ComorbiditiesNo comorbidities1.001.00
11.620.82 to 3.210.1660.790.63 to 0.990.044
2 or more2.251.18 to 4.290.0140.700.55 to 0.880.003
Neutrophil/lymphocyte ratio*<51.001.00
5–104.901.80 to 13.320.0020.720.56 to 0.930.013
>1028.8411.92 to 69.76<0.0010.170.12 to 0.26<0.001
Platelet count* (×109/L)<1006.883.61 to 13.13<0.0010.160.05 to 0.490.001
≥1001.001.00
SOFA score*1.631.54 to 1.74<0.0010.620.57 to 0.67<0.001
D-dimer (mg/L)†<0.51.001.00
0.5–1.01.530.63 to 3.670.3460.820.64 to 1.060.129
>1.03.341.55 to 7.190.0020.570.45 to 0.73<0.001
Ferritin (ng/mL)†<5001.001.00
≥5004.112.28 to 7.41<0.0010.520.42 to 0.64<0.001
CRP† (mg/L)1.00030.999 to 1.0010.0800.990.99 to 1.000.360
LDH† (IU/L)<4501.001.00
≥4504.882.72 to 8.75<0.0010.530.43 to 0.66<0.001
PaO2/FiO2*<100 (severe)25.6414.8 to 44.41<0.0016.5e-084.3e-08 to 9.9e-08<0.001
100–200 (moderate)5.973.05 to 11.69<0.0010.190.10 to 0.36<0.001
>200 (mild)1.001.00
Interval from onset of symptoms to admission1.050.96 to 1.140.3340.970.94 to 1.000.058
Vasopressor support11.367.79 to 16.56<0.0010.030.004 to 0.220.001
Invasive ventilation support19.5712.21 to 31.35<0.0010.010.002 to 0.09<0.001
  • P values are highlighted in bold for statistically significant factors.

  • *Laboratory parameters were measured at days 0, 1, 3, 5, 7 and day 14.

  • †Inflammatory biomarker values were measured at days 0, 3 and day 7.

  • CRP, C-reactive protein; LDH, lactate dehydrogenase; SHR, subdistribution HR; SOFA, Sequential Organ Failure Assessment.