Overview of models including adjustment for risk factors in each model
| Covariates | Model 1 | Model 2* | Model 3† |
| Demographic | Age | Age | Age |
| Sex | Sex | Sex | |
| Lifestyle | Smoking | Smoking | |
| Education | Education | ||
| Alcohol | Alcohol | ||
| Waist circumference | Waist circumference | ||
| Body fat percentage | Body fat percentage | ||
| Physical activity | Physical activity | ||
| Hormonal | Early menopause | ||
| Breast feeding | |||
| Hormone replacement therapy | |||
| Oral contraception | |||
| Parity |
*Model 2 will be considered the main analysis.
†Model 3 will be performed as a sex-specific supplemented analyses in women only.