Table 7

Multivariate linear regression model—impact of FORTA, PRISCUS and EU(7)-PIM use on cognitive skills measured by LDST

LDSTCorrelation coefficientP value95% CI
FORTA PIM per patient−0.3060.022−0.567 to −0.044
PRISCUS PIM per patient−0.1180.428−0.652 to 0.276
EU(7)-PIM per patient−0.1880.168−0.416 to 0.072
Age−0.172<0.001−0.384 to −0.296
Sex−0.340<0.0012.114 to 3.050
CASMIN3_22.334<0.0011.799 to 2.869
CASMIN3_33.784<0.0013.000 to 4.567
Income2.406<0.0011.868 to 2.943
Number of diseases weighted by severity−0.121<0.001−0.170 to −0.073
Number of taken drugs−0.0040.921−0.081 to 0.073
  • Dependent variable: results from LDST; independent variables: FORTA PIM, PRISCUS PIM, EU(7)-PIM; covariables included in the regression model: sex, age, education standard (casmin3_2: comparison between medium and low educational standard, casmin3_3: comparison between high and low educational standard), number of diseases weighted by severity, income and number of taken drugs.

  • All three PIM lists are included in one regression model.

  • FORTA, Fit fOR The Aged; LDST, letter digit substitution test; PIM, potentially inappropriate medication.