Table 3

StO2 measures as predictors for higher peak hsTnT and MINS

 StO2 indices High peak hsTnT versus low peak hsTnT MINS versus no MINS UnivariableOR (95% CI) P value MultivariableOR (95% CI) P value UnivariableOR (95% CI) P value Median SmO2, % 0.93 (0.87 to 0.996) 0.039 0.92 (0.82 to 1.04) 0.18 0.96 (0.76 to 1.21) 0.75 Minimum SmO2, % 0.97 (0.92 to 1.01) 0.16 0.94 (0.86 to 1.03) 0.20 0.95 (0.75 to 1.22) 0.70 Maximum SmO2, % 0.92 (0.85 to 0.99) 0.025 0.90 (0.80 to 1.02) 0.11 0.90 (0.70 to 1.15) 0.41 TW AUC SmO2, %×min×h-1 1.00 (1.00 to 1.00) 0.15 1.00 (1.00 to 1.01) 0.22 1.00 (0.99 to 1.01) 0.74 Median ScO2, % 0.99 (0.91 to 1.06) 0.70 0.92 (0.79 to 1.06) 0.24 0.79 (0.59 to 1.07) 0.13 Minimum ScO2, % 0.96 (0.91 to 1.03) 0.26 0.83 (0.69 to 0.98) 0.030 0.10 (0.00 to 5.34) 0.26 Maximum ScO2, % 0.97 (0.90 to 1.05) 0.47 0.99 (0.94 to 1.05) 0.82 1.01 (0.96 to 1.06) 0.76 TW AUC ScO2, %×min×h-1 1.00 (1.00 to 1.01) 0.32 1.00 (1.00 to 1.01) 0.33 1.00 (1.00 to 1.01) 0.32
• This table shows the odds of having an outcome (high peak hsTnT or MINS, respectively) for every 1%/one unit increase in the specific StO2 variable. Multivariable analysis is adjusted for age, sex, BMI, smoking, diabetes, hypertension, previous stroke, chronic lung disease, arrhythmia, valvular disease, chronic kidney disease, length of surgery, osteotomy performed, estimated blood loss, mean arterial blood pressure and mean heart rate.

• BMI, body mass index; hsTnT, high-sensitivity troponin T; MINS, myocardial injury after non-cardiac surgery; ScO2, cerebral tissue oxygenation; SmO2, skeletal muscle tissue oxygenation; StO2, tissue oxygenation; TW AUC, time-weighted area under the curve.