Table 1

Summary of assessment measures to be completed at each time point

MeasureData collectedInformant/sourceBaseline12 months24 months
Demographics/backgroundCaregiver: age, gender, education, occupation, sexual orientation, ethnicity and relationship to child.
CYP: age, sex assigned at birth, ethnicity, age at referral and background to referral.
Gender identity
Parent QuestionnaireDSM-5 criteria for gender dysphoria in child; family experiences of child’s gender identity; gender expression and social transition; and body image and body distress.P×××
Child Semi-Structured InterviewVerbal identification with experienced gender; gender expression and social transition; age first realised and expressed gender identity; and body image and distress.C×××
Young Person QuestionnaireDSM-5 criteria for gender dysphoria; distress around gender identity; gender expression and social transition; body image and body distress; and sexual orientation.YP×××
Gender Similarity Task28Perceived similarity to own-gender and other-gender peers.C×××
Gender Diversity Questionnaire7Verbal identification with expressed gender; gender fluidity; gender expression; age first realised and expressed gender identity.YP×××
Utrecht Gender Dysphoria Scale29Severity of gender dysphoria.YP×××
Gender Identity Self Stigma Scale30Internalised transphobia and stigma.YP×××
CYP functioning
Child Behaviour Checklist31Emotional reactivity; anxious/depressed; somatic complaints; withdrawn; sleep problems; attention problems; and aggressive behaviour.P×××
Autism Quotient32Autistic traits in child or adolescent.P×××
Strengths and Difficulties Questionnaire33Emotional symptoms; conduct problems; hyperactivity/inattention; peer relationship problems; and prosocial behaviour.P and YP×××
Youth Self Report31Anxious-depressed; withdrawn/depressed; somatic complaints; social problems; thought problems; attention problems; rule-breaking behaviour; and aggressive behaviour.YP×××
Moods and Feelings Questionnaire34Depressive symptoms in child or adolescent.YP×××
Warwick-Edinburgh Mental Well-being Scale35Mental well-being.YP×××
Child and Youth Resilience Measure36Brief screener for resilience processes in the lives of children and adolescents.C and YP×××
Healthcare resource use
Child & Adolescent Service Use Schedule37All-cause uses of hospital, community-based and private health and social care services.P×××
Quality of life
Kidscreen-5238Physical well-being, psychological well-being, moods and emotions, self-perception, autonomy, parent relations and home life, social support and peers, school environment, social acceptance (bullying), and financial resources.P or C, YP×××
Child Health Utility 9 Dimensions39Paediatric health-related quality of life for use in economic evaluation (quality adjusted life years).P or C, YP×××
Physical measures
Parental heightHeight in centimetres.P×
CYP pubertal developmentTanner stage.P and YP×××
CYP height, weight, BMIHeight in centimetres; weight in kilograms.P and YP×××
  • Child (C) ages for data collection are 3–11 years. Young people (YP) ages for data collection are ≥12 years. Parental (P) proxy measures are available for children (aged <8 years) not able to self-complete quality of life instruments.

  • BMI, body mass index; CYP, children and young people.