Final multivariable analysis for HAs after 6 months of follow-up
| Prognostic variable | Estimate | SE | P value |
| Global intercept* | −1.641 | 0.616 | 0.008 |
| Age (per year) | −0.010 | 0.008 | 0.220 |
| Sex (male) | 0.226 | 0.096 | 0.016 |
| Medication count† | 0.034 | 0.016 | 0.032 |
| START criteria count‡ | 0.080 | 0.036 | 0.028 |
| STOPP criteria count§ | 0.073 | 0.038 | 0.056 |
| Physical Component Summary score (PCS) from health-related quality of life Comorbidity Index¶ | 0.013 | 0.015 | 0.373 |
| HAs at baseline** | 0.376 | 0.053 | <0.001 |
*In addition to the study-specific intercept (baseline risks): ISCOPE (0.510), Opti-Med (−0.242), PRIMUM (−0.248), RIME (−0.020).
†Medication count is operationalised as (anatomical therapeutic chemical classification system) 7-digit codes are used for chronic medication as defined per trial including medication for external use.
‡START criteria included START A3, A5-A8, B1, B2, C1, C2, E1-E4, E7 and F1.
§STOPP criteria included STOPP B1-B3, B10, B12, B13, C6, C7, C10, C11, D2, D5-D7, D14, F1, G1, G2, H2-H5, H7, H8, J1-J3, K1-K4 and M1.
¶PCS was calculated according to the modified instrument: maximum count 12 conditions, 47 points.
**Hospital admissions at baseline were absolute number of previous hospital admissions (in the 12 months preceding baseline).
HA, hospital admissions.