Association between allostatic load and mortality among males and females
| Males (N=709) | ||||
| Events per 1000 PYs (95% CI) | Unadjusted | Demographically adjusted* | Fully adjusted† | |
| HR (95% CI) | ||||
| AL (continuously) | 1.75 (1.44 to 2.12) | 1.51 (1.24 to 1.84) | 1.51 (1.23 to 1.84) | |
| AL category | ||||
| Low (0–1) | 66.1 (50.7 to 86.1) | Ref. | Ref. | Ref. |
| Medium (2–4) | 110.4 (96.3 to 126.7) | 1.68 (1.24 to 2.26) | 1.36 (1.00 to 1.83) | 1.33 (0.98 to 1.80) |
| High (5–9) | 201.3 (153.0 to 265.0) | 3.06 (2.09 to 4.48) | 2.29 (1.56 to 3.37) | 2.18 (1.48 to 3.22) |
| Females (N=810) | ||||
| | Events per 1000 PYs (95% CI) | Unadjusted | Demographically adjusted* | Fully adjusted† |
| HR (95% CI) | ||||
| AL (continuously) | 1.45 (1.23 to 1.72) | 1.16 (0.97 to 1.37) | 1.16 (0.97 to 1.38) | |
| AL category | ||||
| Low (0–1) | 121.1 (100.7 to 145.6) | Ref. | Ref. | Ref. |
| Medium (2–4) | 174.8 (156.9 to 194.7) | 1.44 (1.17 to 1.79) | 1.14 (0.92 to 1.42) | 1.11 (0.89 to 1.38) |
| High (5–9) | 252.6 (180.5 to 353.5) | 2.11 (1.44 to 3.10) | 1.36 (0.93 to 2.01) | 1.34 (0.91 to 1.97) |
*Demographically adjusted model included age, ethnicity (Han vs minority), education (any vs none), and marital status (married vs others).
†Fully adjusted model included age, ethnicity (Han vs minority), education (any vs none) and marital status (married vs others), smoking (current vs previous or non-smoke), exercise (yes vs no) and chronic diseases such as pulmonary disease and arthritis.
AL, allostatic load; PY, person-year.