Patient outcomes comparing low doses of oxygen supplementation with high doses of oxygen supplementation
| Reference | Low-dose oxygen | High-dose oxygen | RR (95% CI) |
| Atelectasis | |||
| Akca et al15 | 9 (64%) | 15 (94%) | 1.46 (0.97 to 2.2) |
| Asfar et al22 | 13 (6%) | 26 (12%) | 2.0 (1.06 to 3.79) |
| Benoît et al26 | 2.5% of total surface | 7% of total surface | – |
| Ishii et al18 | 64% of patients | 76.8% of patients | – |
| Lång et al24 | 14 (52%) | 18 (47%) | 0.914 (0.56 to 1.5) |
| Rothen et al8 | 0.25 cm2 ±0.4 | 4.2 cm2 ±5.6 | – |
| Staehr et al25 | 2 (13.3%) | 5 (25%) | 1.88 (0.42 to 8.37) |
| Suzuki et al21 | TWA AS=1.5 (0.7–2) | TWA AS=2 (1.2–2.2) | – |
| ARDS | |||
| Lång et al24 | 3 (11%) | 0 (0%) | – |
| Panwar et al14 | 11 (32%) | 11 (28%) | 0.87 (0.43 to 1.75) |
| Pneumonia | |||
| Asfar et al22 | 32 (15%) | 30 (14%) | 0.94 (0.59 to 1.49) |
| Barrot et al23 | 17 (17.2%) | 22 (21.6%) | 1.26 (0.71 to 2.22) |
| Lång et al24 | 6 (22.2%) | 6 (15.8%) | 0.71 (0.26 to 1.97) |
| Staehr-Rye et al19 | 104 (0.7%) | 227 (1.9%) | 2.83 (2.25 to 3.56) |
| Duration of mechanical ventilation | |||
| Lång et al24 | 6.3 days (4.7–10) | 5 days (2.5–7.5) | – |
| Rachmale et al20 | 2.8 days1–6 | 6 days (3–10.5) | – |
Continuous data are presented as mean (SD) or median (IQR). RR is presented with high-dose oxygen in the numerator.
ARDS, acute respiratory distress syndrome; RR, relative risk; TWA AS, time-weighted average atelectasis.