Number of drugs | Type of drug | For orphan disease | First-in-class | Clinical trial outcome | Anatomical Therapeutic Chemical second level* | Number of patients in pivotal trials (median, IQR)† | |||||
Small molecule | Biologic | Yes | No | Yes | No | Clinical | Surrogate | Antineoplastic | Other | ||
113 | 74 | 39 | 46 | 67 | 32 | 81 | 56 | 57 | 30 | 82 | 772 (216– 2300) |
*One drug was not classified.
†Trial size was not available for two drugs.