Table 1

Baseline characteristics of patients

CharacteristicCurrent study number (%; n=270)CARG training cohort (n=500)
Mean age in years (range)69 (65–83)73 (65–91)
Gender
 Female121 (45)281 (56)
 Male149 (55)219 (44)
Comorbidities
 Hypertension114 (42)52%
 Diabetes mellitus71 (26)
 Coronary artery disease12 (4)20%
 Chronic kidney disease3 (1)
Number of comorbidities
 0125 (46)10%
 195 (35)
 ≥250 (19)
Cancer stage
 Stages I–III270 (100)191 (38)
 Undergone resection210 (78)
ECOG performance status (clinician assessed)
 0/1230 (85)402 (80) *
 240 (15)86 (17) †
Factors assessed in CARG
 Age ≥72 years60 (22)270 (54)
 Cancer type GI or Genitourinary212 (79)185 (37)
 Chemotherapy dosing, standard dose205 (76)380 (76)
 No. of chemotherapy drugs, polychemotherapy194 (72)351 (70)
 Haemoglobin <110 g/L (male),<100 g/L (female)99 (37)62 (12)
 Creatinine clearance <34 mL/min5 (2)44 (9)
 Hearing, fair or worse19 (7)123 (25)
 No. of falls in last 6 months, 1 or more18 (7)91 (18)
 IADL: Taking medications, with some help/unable29 (11)39 (8)
 MOS: Walking 1 block, somewhat limited/limited a lot17 (6)109 (22)
 MOS: Decreased social activity because of physical/emotional health, limited at least sometimes18 (7)218 (44)
 Median overall risk score67
Risk stratification
 Low risk (0–5 points)72 (27)128 (26)
 Intermediate risk (6–9 points)164 (61)227 (45)
 High risk (10–19 points)34 (13)109 (22)
Age-adjusted Charlson’s Comorbidity Index
 ≤4111 (41)
 >4159 (59)
  • *Equivalent to KPS ≥80.

  • †Equivalent to KPS 60–70.

  • CARG, Cancer Aging Research Group; GI, gastrointestinal; IADL, Instrumental activities of daily living; KPS, Karanofsky Performance Status.